Poly(lactic acid)-PLA: An Analysis Based on Literature Text Mining





Text mining, PLA, Drug delivery, Biodegradable, Biocompatible, Data mining


The most researched and used biodegradable aliphatic polyester worldwide is poly (lactic acid) - PLA. Due to its inherent properties, PLA is a leading biomaterial for several and numerous applications and the most promising biopolymer capable of replacing conventional petroleum-derived polymers. Besides, PLA is also one of the most promising candidates for new developments in the traditional sectors such as packaging and the automotive industry, in the electronics industry, and the biomedical area. To verify the importance of drug release in the various applications of PLA, a text mining of the last ten years was carried out. The text-mining tool was used to identify this polymer's main applications in the last ten years, allowing us to draw a map year by year based on correlation analysis. Firstly, an analysis was made of the main applications of PLA in scientific research, by searching for "PLA", in the ScienceDirect scientific base (https://www.sciencedirect.com/) and using the online tool Voyant Tools. Some words related to drug release were selected, checking how many times they were mentioned over the years. In this way, it was possible to see which years were the most and least used PLA in drug release. It was not possible to observe a gradual increase or decrease in this polymer's use, for this purpose, over time. The text mining presented here proved to be an efficient and fast way to observe the desired theme.

Author Biography

Fernando Gomes de Souza Junior, Universidade Federal do Rio de Janeiro

Associate (III) Prof. Fernando Gomes: Expertise focused in the use of renewable resources and nanocomposites in sensors, drug delivery and environmental recovery. Coordination of more than ten research projects with financial support from Brazilian government sponsoring agencies. Published 160 scientific articles plus 13 accepted for publication during 2021. Published 8 books. Among them,3 chemistry books in Portuguese and 3 books about Biopolymers in English. He has published more than two hundred papers in Conferences and Scientific meetings. Co-convener of the Sixth International Conference on Natural Polymers, Biopolymers and biomaterials: Applications from macro to nanoscale (http://www.biopolymers.macromol.in/), Chairman of the Fifth International Conference on Natural Polymers, Biopolymers and biomaterials: Applications from macro to nanoscale (https://www.icnp2017rio.com/) and Chaiman of the 1st Brazilian Conference on Design of Experiments and Data Analysis (https://sites.google.com/pent.coppe.ufrj.br/conbrapa2020). Supervisor of 128 undergraduate students; 29 M.Sc. students, 14 Ph.D. students and 6 Post Doc. Nowadays I am the supervisor of 11 undergraduate students; 7 M.Sc. students, 10 Ph.D. students and 3 Post Doc. Associate Editor of the MedCrave Online Journal (MOJ) Polymer Science (ISSN: 2574-9773) since 2017. Editor of the Academic Journal of Polymer Science (ISSN: 2641-8282), since 2018. Member of the Editorial Board of Composite Interfaces (ISSN: 0927-6440), since 2021. Member of the editorial board of Current Applied Polymer Science (ISSN 2452-2716) since 2016 and Editor-in-Chief of Current Applied Polymer Science (ISSN 2452-2716) since 2020. Professor Gomes has founded the Brazilian Journal of Experimental Design, Data Analysis and Inferential Statistics in 2021, acting as its 1st Editor-in-Chief. Awardedtwice as Young Scientist of Rio de Janeiro State (FAPERJ 2011 and 2014), Chair Professorship on Nanoscience and Nanotechnology - Mahatma Gandhi University – India (2018), member of Post Graduate Program in Science and Technology of Polymers of the Macromolecules Institute / Federal University of Rio de Janeiro (UFRJ) since 2008, member of Post Graduate Program in Civil Engineering (COPPE/UFRJ) between 2015-2019 and member of Post Graduate Program in Nanotechnology (COPPE/UFRJ) since 2019.